Hepatocyte Growth Factor Is Positively Associated With Risk of Stroke
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چکیده
منابع مشابه
Hepatocyte Growth Factor Is Positively Associated With Risk of Stroke
The protein hepatocyte growth factor (HGF) and its receptor c-Met are produced in response to tissue injury and are functional in tissue repair mechanisms. Their favorable effects in the heart and vasculature include anti-inflammatory, antifibrotic, and proangiogenic actions. Because HGF is released in response to endothelial injury, higher levels of circulating HGF are associated with hyperten...
متن کاملHepatocyte Growth Factor Is Positively Associated With Risk of Stroke: The MESA (Multi-Ethnic Study of Atherosclerosis).
BACKGROUND AND PURPOSE Hepatocyte growth factor (HGF) is positively associated with ischemic and hemorrhagic stroke risk factors. However, understanding the relation between HGF and stroke is in its infancy. Therefore, we sought to examine the association of circulating HGF with incident stroke using data from the MESA (Multi-Ethnic Study of Atherosclerosis). We hypothesized that circulating HG...
متن کاملObesity is associated with increased levels of circulating hepatocyte growth factor.
OBJECTIVES This study evaluated whether obesity in humans was associated with an increase in circulating hepatocyte growth factor (HGF) and vascular endothelial growth factor (VEGF) levels. BACKGROUND Obesity acts as a cardiovascular risk factor by mechanisms that are not fully understood. Adipose tissue is able to secrete multiple cytokines and growth factors ex vivo. We hypothesized that th...
متن کاملHepatocyte Growth Factor and the Risk of Ischemic Stroke Developing Among Postmenopausal Women
Background and Purpose—Hepatocyte growth factor (HGF) is a potent angiogenic factor and may play a role in the development and progression of atherosclerotic lesions, the underlying mechanism of cardiovascular disease. However, there have been no prospective studies examining the relationship between HGF levels and risk of stroke. Methods—We conducted a nested case-control study (972 incident s...
متن کاملEstablishment of human hair follicle mesenchymal stem cells with overexpressed human hepatocyte growth factor
Objective(s): Chronic liver disease has become a major health problem that causes serious damage to human health. Since the existing treatment effect was not ideal, we need to seek new treatment methods. Materials and Methods: We utilized the gene recombination technology to obtain the human hair mesenchymal stem cells which overexpression of human hepatocyte growth factor (hHGF). Furthermore, ...
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ژورنال
عنوان ژورنال: Stroke
سال: 2016
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.116.014172